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 Table of Contents  
ORIGINAL HYPOTHESIS
Year : 2017  |  Volume : 8  |  Issue : 2  |  Page : 46-47

Potential causative role of involuntary mouth opening in temporomandibular disorders


1 Department of Physiology, Tokyo Dental College, Chiyoda-ku, Tokyo, Japan
2 Department of Epidemiology and Public Health, Tokyo Dental College, Chiyoda-ku, Tokyo, Japan

Date of Web Publication11-May-2017

Correspondence Address:
Yuki Kojima
Department of Physiology, Tokyo Dental College, Chiyoda-ku, Tokyo
Japan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/denthyp.denthyp_4_17

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  Abstract 

Introduction: Bruxism has long been suspected as a cause of temporomandibular disorders (TMDs). However, the validity of conventional guidelines and treatment has been discussed since sometime. The association between bruxism and TMDs has recently been questioned, as self-assessments of bruxism are somewhat unreliable, and bruxism appears to have no adverse effects based on histological and physiological findings. The hypothesis: We hypothesize that involuntary mouth opening may play a role in the development of TMDs. Evaluation of the Hypothesis: Recently, some clinical and basic reports have indicated that involuntary mouth opening might be associated with TMDs.

Keywords: Causality, muscle, skeletal, temporomandibular joint disorders


How to cite this article:
Kojima Y, Suzuki S, Sugihara N. Potential causative role of involuntary mouth opening in temporomandibular disorders. Dent Hypotheses 2017;8:46-7

How to cite this URL:
Kojima Y, Suzuki S, Sugihara N. Potential causative role of involuntary mouth opening in temporomandibular disorders. Dent Hypotheses [serial online] 2017 [cited 2017 May 24];8:46-7. Available from: http://www.dentalhypotheses.com/text.asp?2017/8/2/46/206102


  Introduction Top


Bruxism, in which the teeth are gnashed or clenched, has been proposed as a cause of temporomandibular disorders (TMDs), as the condition places high stress on the temporomandibular joint, similar to malocclusion.[1],[2] In the past, if patients without malocclusion reported feeling fatigue and pain around the temporomandibular joint upon waking, the cause of TMD was typically diagnosed as bruxism. Although the causal association between bruxism and TMDs remained unknown for quite some time, dentists have begun to recognize the importance of occlusal splints for buffering against bruxism in self-diagnosed patients.[3],[4]


  The Hypothesis Top


Some clinical reports have indicated that obstructive sleep apnea syndrome (OSAS) is associated with TMDs. One prospective cohort study of adults aged 18–44 years reported that OSAS preceded the initial onset of TMDs, based on an affirmative response to “difficulty in opening the mouth.”[5] In a large-scale self-assessment survey including 5,820 respondents, researchers observed that individuals who were at risk for OSAS also experienced symptoms of TMDs.[6] Additional studies have reported a tendency towards mouth breathing in patients with OSAS.[7],[8] Based on these clinical observations, we hypothesized that involuntary mouth opening might cause TMDs.


  Evaluation of the Hypothesis Top


TMDs, including myofascial pain, were first described in the mid-nineteenth century,[9] while an association between TMDs and occlusion has been discussed since the 1920s.[10],[11] In 1934, treatment of improper prostheses such as dentures and crowns resulted in TMD improvement in 11 cases.[12] At this time, many patients with abnormalities of the temporomandibular joint exhibited infraocclusion, and symptoms of TMD were relieved following restoration of proper bite alignment, suggesting that TMDs were associated with malocclusion.

The “Diagnostic Criteria for Temporomandibular Disorders” (DC/TMD) include guidelines based on evidence obtained from several studies and advanced diagnostic imaging.[13] Published in 2014, the DC/TMD suggested new criteria for the classification of TMDs, including myofascial pain. This report discussed the validity of the conventional guidelines and treatment, and brought the association between bruxism and TMDs into question. However, some researchers have recently reported findings that do not support the notion that bruxism is a cause of TMDs.

The negative evidence can be broadly classified into two groups. First, patients’ self-assessment scores exhibited low reliability, despite the use of clear factors for diagnosis. Although polysomnography (PSG) is needed for a definitive diagnosis of bruxism, the procedure is costly, and doctors tend to rely on self-reports from individual patients. Indeed, many patients with self-reported bruxism did not meet criteria for diagnosis when examined via PSG.[14] Furthermore, bruxism is characterized by attrition of the teeth and teeth marks on the buccal mucosa, and a previous study reported no significant difference between self-reported and PSG-identified bruxism in terms of these clinical findings.[15] Second, bruxism appears to have no adverse effects in terms of physiology: in humans experiencing bruxism for 2 h/day over 3 days, pain tends to be acute, local, and to dissipate within 5 min.[16] These results suggest that bruxism may not result in damage to the muscle at a cellular level. These findings therefore raise concern regarding the true cause of TMDs. Many patients with TMDs do not exhibit malocclusion, suggesting that factors other than bruxism may cause or worsen TMDs.

A previous study has reported that while the morphology of samples from isometric contraction and passive stretch groups appeared normal, samples from eccentrically exercised rabbit skeletal muscles exhibited abnormally large fibers when viewed in cross section. When rabbit skeletal muscle was subjected to continuous isometric contraction, which is equivalent to masticatory muscle contraction during bruxism, no damage to the muscle tissue was observed.[17] In addition, continuous eccentric contractions, which are equivalent to opening the mouth, resulted in damage to fiber structures in rabbit skeletal muscle.[17] This exercise style is the reverse of the action experienced during bruxism. These results suggest that involuntary mouth opening might influence TMDs.


  Conclusion Top


Based on previous scientific observations, we hypothesize that involuntary mouth opening might cause TMDs. Therefore, we suggest that involuntary mouth opening might be a new etiology for TMDs. As there is currently no published evidence regarding the association between TMDs and involuntary mouth opening, we suggest that both baseline and epidemiological studies be performed to evaluate this hypothesis.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Glaros AG, Rao SM. Effects of bruxism: A review of the literature. J Prosthet Dent 1977;38:149-57.  Back to cited text no. 1
    
2.
Attanasio R. Nocturnal bruxism and its clinical management. Dent Clin North Am 1991;35:245-52.  Back to cited text no. 2
    
3.
Dahlström L, Haraldson T. Bite plates and stabilization splints in mandibular dysfunction: a clinical and electromyographic comparison. Acta Odontol Scand 1985;43:109-14.  Back to cited text no. 3
    
4.
Kawazoe Y, Kotani H, Hamada T, Yamada S. Effect of occlusal splints on the electromyographic activities of masseter muscles during maximum clenching in patients with myofascial pain-dysfunction syndrome. J Prosthet Dent 1980;43:578-80.  Back to cited text no. 4
    
5.
Sanders AE, Essick GK, Fillingim R, Knott C, Ohrbach R, Greenspan JD et al. Sleep apnea symptoms and risk of temporomandibular disorder: OPPERA cohort. J Dent Res 2013;92(Suppl):70S-7.  Back to cited text no. 5
    
6.
Suzuki S, Kojima Y, Takayanagi A, Yoshino K, Ishizuka Y, Satou R et al. Relationship between obstructive sleep apnea and self-assessed oral health status: An internet survey. Bull Tokyo Dent Coll 2016;57:175-81.  Back to cited text no. 6
    
7.
Koutsourelakis I, Vagiakis E, Roussos C, Zakynthinos S. Obstructive sleep apnoea and oral breathing in patients free of nasal obstruction. Eur Respir J 2006;28:1222-8.  Back to cited text no. 7
    
8.
Oeverland B, Akre H, Skatvedt O. Oral breathing in patients with sleep-related breathing disorders. Acta Otolaryngol 2002;122:651-4.  Back to cited text no. 8
    
9.
Cooper A. A Treatise on Dislocations and on Fractures of the Joints. 2nd ed. London: Langman; 1823. p. 393.  Back to cited text no. 9
    
10.
Wright WH. Deafness as influenced by malposition of the jaws. J Natl Dent Assoc 1920;7:979-92.  Back to cited text no. 10
    
11.
Monson GS. Impaired function as a result of closed bite. J Am Dent Assoc 1921;8:833-9.  Back to cited text no. 11
    
12.
Costen JB. A syndrome of ear and sinus symptoms dependent upon disturbed function of the temporomandibular joint. Ann Otol Rhin Laryng 1934;43(Pt 1):1-15.  Back to cited text no. 12
    
13.
Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP et al. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache 2014;28:6-27.  Back to cited text no. 13
    
14.
Kronfli T, Bellinger K, Grace E, Sarlani E, Whang K, Buenaver L et al. Sleep disorders in temporomandibular joint disorders. Sleep Biol Rhythms 2007;5:A190.  Back to cited text no. 14
    
15.
Nakae K, Yatani H, Ishigaki S, Uchida M, Sumiya M, Inano S. Construct validity of perceived tooth grinding for sleep bruxism in TMD patients. J Jpn Soc TMJ 2009;2:209-15.  Back to cited text no. 15
    
16.
Takeuchi T. Symptoms and physiological responses to prolonged, repeated, low-level tooth clenching in humans. Headache 2015;55:381-94.  Back to cited text no. 16
    
17.
Lieber RL. Muscle damage induced by eccentric contractions of 25% strain. J Appl Physiol 1991;70:2498-507.  Back to cited text no. 17
    




 

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Abstract
Introduction
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Conclusion
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