Dental Hypotheses

SYSTEMATIC REVIEW
Year
: 2015  |  Volume : 6  |  Issue : 4  |  Page : 129--133

Assessment of blinding success among dental implant clinical trials: A systematic review


Jafar Kolahi1, Saber Khazaei2 
1 Independent Research Scientist, Founder and Managing Editor of Dental Hypotheses, Isfahan, Iran
2 Department of Research, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran

Correspondence Address:
Jafar Kolahi
N 24, Pardis, Shahin Shahr, Isfahan - 8317918981
Iran

Introduction: It is widely believed that blinding is a cornerstone of randomized clinical trials and that significant bias may result from unsuccessful blinding. However, it is not enough to claim that a clinical trial is single- or double-blinded and that assessment of the success of blinding is ideal. The aim of this study was to evaluate the prevalence of assessment of blinding success among dental implant clinical trials and to introduce methods of blinding assessment to the implant research community. Methods: In November 2014, PubMed was searched by blinded and experienced researchers with the query DQimplant AND (blind* OR mask*)DQ using the following filters: (1) Article type: clinical trial; (2) Journal categories: dental journals; (3) Field: title/abstract. Consequently, title/abstract was reviewed in all relevant articles to find any attempt to assess the success of blinding in dental implant clinical trials. Results: The PubMed search results yielded 86 clinical trials. The point of interest is that when DQblind* OR mask*DQ was deleted from the query, the number of results increased to 1688 clinical trials. This shows that only 5% of dental implant clinical trials tried to use blinding. Disappointingly, we could not find any dental implant clinical trial reporting any attempt to assess the success of blinding. Conclusion: The current status of turning a blind eye to unblinding in dental implant clinical trials is not tolerable and needs to be improved. Researchers, protocol reviewers, local ethical committees, journal reviewers, and editors should make a concerted effort to incorporate, report, and publish such information to understand its potential impact on study results.


How to cite this article:
Kolahi J, Khazaei S. Assessment of blinding success among dental implant clinical trials: A systematic review.Dent Hypotheses 2015;6:129-133


How to cite this URL:
Kolahi J, Khazaei S. Assessment of blinding success among dental implant clinical trials: A systematic review. Dent Hypotheses [serial online] 2015 [cited 2020 Aug 14 ];6:129-133
Available from: http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2015;volume=6;issue=4;spage=129;epage=133;aulast=Kolahi;type=0